Chondroitin sulfate
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چکیده
While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy.
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Investigation on Counterfeit Glucosamine and Chondroitin Products in Iranian Pharmaceutical Markets
The purpose of this report is to present the results of analysis of actual glucosamine and/or chondroitin contents of several such products in the market place and to determine if they significantly deviate from their label claim. A total of fourteen products containing glucosamine sulfate and nine products containing chondroitin sulfate were evaluated. The amounts of glucosamine and chondroiti...
متن کاملInvestigation on Counterfeit Glucosamine and Chondroitin Products in Iranian Pharmaceutical Markets
The purpose of this report is to present the results of analysis of actual glucosamine and/or chondroitin contents of several such products in the market place and to determine if they significantly deviate from their label claim. A total of fourteen products containing glucosamine sulfate and nine products containing chondroitin sulfate were evaluated. The amounts of glucosamine and chondroiti...
متن کاملEffect of Chondroitinase ABC Enzyme on Glial Fibrillary Acidic Protein, Chondroitin Sulfated Proteoglycans and Chondroitin 4-Sulfate Levels in an Animal Model of Spinal Cord Injury
Background: Following spinal cord injury, reactive astrocytes upregulate chondroitin sulfate proteoglycans (CSPGs) which act as a barrier to neuronal repair and regeneration. Therefore, enzymatic digestion of CSPGs by chondroitinase ABC (cABC) is a key strategy in the treatment of spinal cord injury. Furthermore, cABC has been shown to attenuate post spinal cord injury inflamma...
متن کاملDecellularized kidney in the presence of chondroitin sulfate as a natural 3D scaffold for stem cells
Objective(s): Use of biological scaffolds and automating the cells directing process with materials such as growth factors and glycosaminoglycans (GAGs) in a certain path may have beneficial effects in tissue engineering and regenerative medicine in future. In this research, chondroitin sulfate sodium was used for impregnation of the scaffolds. It is a critical component in extracellular matrix...
متن کاملDevelopment of affinity-based delivery of NGF from a chondroitin sulfate biomaterial
Chondroitin sulfate is a major component of the extracellular matrix in both the central and peripheral nervous systems. Chondroitin sulfate is upregulated at injury, thus methods to promote neurite extension through chondroitin sulfate-rich matrices and synthetic scaffolds are needed. We describe the use of both chondroitin sulfate and a novel chondroitin sulfate-binding peptide to control the...
متن کاملGlycosaminoglycan Production by Bovine Aortic Endothelial
Bovine aortic endothelial cells were cultured in medium containing [3H]glucosamine and concentrations of [“S]sulfate ranging from 0.01 to 0.31 mM. While the amount of [‘H]hexosamine incorporated into chondroitin sulfate and heparan sulfate was constant, decreasing concentrations of sulfate resulted in lower [‘“SIsulfate incorporation. Sulfate concentrations greater than 0.1 1 mM were required ...
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